Yangge Biotech supplies high-quality Berberine Hydrochloride Powder 97%, a premium botanical alkaloid extracted and purified using advanced manufacturing technology. Our berberine hydrochloride features high purity, excellent stability, and consistent quality, making it suitable for dietary supplements, functional foods, pharmaceutical research, and nutraceutical formulations. Every batch is manufactured under strict quality control standards to ensure purity, safety, and reliable performance.

What Is Berberine Hydrochloride?

Berberine Hydrochloride is a purified form of berberine, a naturally occurring isoquinoline alkaloid found in several medicinal plants, including Coptis chinensis (Goldthread), Phellodendron amurense (Amur Cork Tree), and Berberis species. The hydrochloride (HCl) form is commonly used because it offers excellent stability, high purity, and good water solubility, making it ideal for dietary supplements and nutraceutical formulations.

Berberine Hydrochloride Powder is typically standardized to 97% or 98% purity using High-Performance Liquid Chromatography (HPLC). It appears as a yellow crystalline powder and is widely used in capsules, tablets, powders, and functional food products.

Product Specifications

Item	Specification
Product Name	Berberine Hydrochloride Powder
Specification	97%
Appearance	Yellow Crystalline Powder
Active Ingredient	Berberine Hydrochloride
Botanical Source	Phellodendron amurense, Coptis chinensis, or Berberis species
Test Method	HPLC
Solubility	Soluble in water
Shelf Life	24 Months
Storage	Store in a cool, dry place away from direct sunlight

Is Berberine Hydrochloride Safe?

Berberine hydrochloride is generally considered safe for healthy adults when used as directed in dietary supplements or under the guidance of a qualified healthcare professional. It has been widely studied and used for many years in traditional herbal medicine and modern nutritional products.

When manufactured under strict quality standards, berberine hydrochloride is considered a reliable ingredient for dietary supplement formulations. High-quality products undergo rigorous testing to verify identity, purity, potency, heavy metals, microbiological safety, and contaminants.

Safety Considerations

· Manufactured under strict quality control for purity and consistency.

· Widely used in dietary supplements and functional nutrition products.

· May cause mild digestive discomfort (such as stomach upset, constipation, or diarrhea) in some individuals, particularly when first introduced.

· Should not be used during pregnancy or breastfeeding unless advised by a healthcare professional.

· May interact with certain medications, including those used for blood sugar, blood pressure, and blood clotting.

· Individuals with underlying medical conditions or those taking prescription medications should consult a healthcare provider before use.

Note: Berberine hydrochloride is a dietary ingredient and is not intended to diagnose, treat, cure, or prevent any disease. Always follow the recommended dosage and consult a healthcare professional before use if you have medical concerns.

Benefits

· High-purity botanical alkaloid

· Suitable for dietary supplement formulations

· Excellent stability and water solubility

· Commonly used in capsules, tablets, and powders

· Manufactured to strict quality standards

· Consistent batch-to-batch quality

· Ideal for nutraceutical and functional food applications

Applications

Berberine Hydrochloride Powder is widely used in:

· Dietary supplements

· Capsules

· Tablets

· Functional foods

· Nutritional powders

· Herbal formulations

· Pharmaceutical research

· Nutraceutical products

· Functional beverages (where formulation is appropriate)

Certificate of Analysis (COA)

Test Item	Specification	Result
Appearance	Yellow Crystalline Powder	Complies
Assay (HPLC)	≥97%	97.65%
Loss on Drying	≤5.0%	2.12%
Sulfated Ash	≤1.0%	0.36%
Heavy Metals	≤10 ppm	Complies
Lead (Pb)	≤2 ppm	Complies
Arsenic (As)	≤2 ppm	Complies
Cadmium (Cd)	≤1 ppm	Complies
Mercury (Hg)	≤0.1 ppm	Complies
Total Plate Count	<1000 CFU/g	Complies
Yeast & Mold	<100 CFU/g	Complies
E. coli	Negative	Complies
Salmonella	Negative	Complies

Yangge Biotech Third-Party Test Report

Yangge Biotech provides a third-party test report for every batch of Berberine Hydrochloride Powder. Independent laboratories verify assay content, product identity, heavy metals, microbiological safety, residual solvents (where applicable), and overall quality. This testing ensures consistent quality, regulatory compliance, and confidence for customers worldwide.

R&D Capacity

Yangge Biotech has an experienced research and development team dedicated to botanical extracts and nutraceutical ingredients. Equipped with advanced analytical instruments and modern laboratories, our R&D department supports product innovation, formulation optimization, stability studies, and customized ingredient development to meet diverse customer needs.

Certificates

Yangge Biotech operates under internationally recognized quality management systems and can provide certifications according to customer requirements, including:

· GMP

· ISO 9001

· HACCP

· Kosher

· Halal

· FDA Registration (where applicable)

· Third-Party Testing Reports

These certifications demonstrate our commitment to manufacturing excellence, product quality, and international regulatory compliance.

OEM Packing

Yangge Biotech offers comprehensive OEM and private-label manufacturing services.

Packaging options include:

· 100 g aluminum foil bags

· 250 g aluminum foil bags

· 500 g aluminum foil bags

· 1 kg aluminum foil bags

· 5 kg cartons

· 10 kg cartons

· 25 kg fiber drums with double PE inner bags

OEM services include:

· Private labeling

· Custom packaging design

· Formula development

· Bulk ingredient supply

· Retail-ready packaging

· Brand customization

· Global logistics support

Why Choose Us

Premium Botanical Raw Materials

We source carefully selected botanical materials to ensure high-purity berberine hydrochloride with consistent quality.

Strict Quality Control

Every production batch is monitored from raw material inspection through finished product testing to maintain superior quality.

Third-Party Verified

Independent laboratory testing is performed for every batch to verify purity, potency, and safety.

Advanced Manufacturing

Modern production facilities ensure stable supply capacity and consistent manufacturing standards.

Strong R&D Support

Our technical experts provide formulation guidance, technical documentation, and customized product development.

Flexible OEM Solutions

We provide complete OEM and private-label services tailored to your brand and market requirements.

Reliable Global Supply

Yangge Biotech serves customers worldwide with dependable production capacity, export documentation, and professional customer service.

Conclusion

Berberine Hydrochloride Powder 97% is a high-purity botanical ingredient widely used in dietary supplements, nutraceuticals, and functional food formulations. When manufactured under strict quality standards and used as directed, berberine hydrochloride is generally considered safe for healthy adults. Yangge Biotech supplies high-quality Berberine Hydrochloride Powder supported by rigorous quality control, third-party test reports for every batch, advanced R&D capabilities, internationally recognized certifications, and flexible OEM packaging solutions. With reliable manufacturing and professional technical support, Yangge Biotech is a trusted partner for premium botanical ingredients in global markets.

Partner with Yangge for Pharmaceutical-Grade Berberine Hydrochloride Supply

Decisions about where to get materials affect every step of making a product, from making sure the formula is consistent to following rules and making the product successful on the market. Yangge Biotech provides pharmaceutical-grade Berberine hydrochloride that meets the strict requirements of buying pros. Our 98% purity requirement, which was confirmed by HPLC and UV testing, makes sure that each batch is the same, which is important for industrial processes that depend on it. Our wide range of certifications, which includes ISO, HACCP, Kosher, and Halal, shows that we are dedicated to quality excellence and flexible market access.

As a well-known company that makes Berberine hydrochloride, we keep 500 kg of stock on hand so that we can ship orders right away. We also offer flexible 1 kg minimum orders so that we can meet both trial and production-scale needs. Our expert team is here to help you with things like extraction methods, formula optimisation, and regulatory paperwork needs.Contact us or you can email info@yanggebiotech.com to ask for samples, talk about special requirements, or look into business options that could help you improve your product line with traceable, certified raw materials that are backed by strict quality control.

References

1. Yin J, Xing H, Ye J. "Efficacy of berberine in patients with type 2 diabetes mellitus." Metabolism: Clinical and Experimental, 2008; 57(5): 712-717.

2. Dong H, Wang N, Zhao L, Lu F. "Berberine in the treatment of type 2 diabetes mellitus: a systemic review and meta-analysis." Evidence-Based Complementary and Alternative Medicine, 2012; 2012: 591654.

3. Chang W, Chen L, Hatch GM. "Berberine as a therapy for type 2 diabetes and its complications: From mechanism of action to clinical studies." Biochemistry and Cell Biology, 2015; 93(5): 479-486.

4. Derosa G, Maffioli P, Cicero AFG. "Berberine on metabolic and cardiovascular risk factors: an analysis from preclinical evidences to clinical trials." Expert Opinion on Biological Therapy, 2012; 12(8): 1113-1124.

5. Och A, Podgórski R, Nowak R. "Biological activity of berberine—a summary update." Toxins, 2020; 12(11): 713.

6. Spinozzi S, Colliva C, Camborata C, et al. "Berberine and its metabolites: relationship between physicochemical properties and plasma levels after administration to human subjects." Journal of Natural Products, 2014; 77(4): 766-772.