Yangge Biotech supplies high-quality Berberine Hydrochloride Powder manufactured under strict quality control standards to meet the requirements of dietary supplements, pharmaceutical research, and functional food industries. Every batch is carefully tested for purity, identity, heavy metals, microbial contamination, and other quality parameters to ensure consistent performance. With advanced manufacturing facilities, experienced R&D professionals, OEM services, and global certifications, Yangge Biotech is your trusted partner for premium botanical ingredients.

What is Berberine Hydrochloride?

Berberine Hydrochloride is a naturally occurring isoquinoline alkaloid extracted from plants such as barberry, goldenseal, Oregon grape, and Coptis chinensis. It has attracted significant attention due to its potential role in metabolic health, blood glucose management, cardiovascular wellness, and gut microbiome support.

Berberine Hydrochloride is widely used in:

 Dietary supplements

 Functional foods

 Nutraceutical formulations

 Pharmaceutical research

 Health beverages

Product Specifications

Item	Specification
Product Name	Berberine Hydrochloride
Botanical Source	Coptis chinensis / Phellodendron amurense
Appearance	Yellow crystalline powder
Assay	≥97% Berberine HCl (HPLC)
Molecular Formula	C20H18ClNO4
Molecular Weight	371.81
Test Method	HPLC
Solubility	Soluble in water
Shelf Life	24 Months
Storage	Store in a cool, dry place

Benefits of Berberine Hydrochloride

 Supports healthy blood glucose metabolism

 Helps maintain healthy cholesterol levels

 Supports cardiovascular health

 Promotes digestive and gut microbiome balance

 Rich in natural plant alkaloids

 Supports healthy weight management when combined with a balanced lifestyle

 Suitable for dietary supplement formulations

Applications

Berberine Hydrochloride Powder is commonly used in:

 Dietary supplements

 Capsules

 Tablets

 Functional beverages

 Powder drink mixes

 Nutraceutical products

 Scientific research

Certificate of Analysis (COA)

Test Item	Specification	Result
Appearance	Yellow Powder	Pass
Assay (HPLC)	≥97%	97.85%
Identification	Positive	Pass
Loss on Drying	≤5.0%	1.82%
Ash	≤1.0%	0.35%
Heavy Metals	≤10 ppm	Pass
Lead (Pb)	≤2 ppm	Pass
Arsenic (As)	≤2 ppm	Pass
Cadmium (Cd)	≤1 ppm	Pass
Mercury (Hg)	≤0.1 ppm	Pass
Total Plate Count	≤1000 CFU/g	Pass
Yeast & Mold	≤100 CFU/g	Pass
E. coli	Negative	Pass
Salmonella	Negative	Pass

Third-Party Test Report

Yangge Biotech provides a third-party test report for every batch of Berberine Hydrochloride Powder. Independent laboratory testing verifies:

Product identity

Active ingredient assay

Heavy metals

Pesticide residues

Residual solvents

Microbiological safety

This additional level of quality assurance ensures customers receive safe, consistent, and compliant products suitable for international markets.

Research & Development Capacity

Yangge Biotech invests heavily in research and development to continuously improve botanical extraction technology, product purity, and manufacturing efficiency. Our experienced R&D team works closely with customers to develop customized formulations and innovative ingredient solutions for dietary supplements, functional foods, and pharmaceutical applications.

Our R&D capabilities include:

 Advanced extraction technology

 Product formulation support

 Stability testing

 Customized ingredient development

 Technical documentation assistance

 Continuous product innovation

Certificates

Yangge Biotech maintains strict international quality management systems and complies with global manufacturing standards.

Available certifications may include:

 GMP Certified

 ISO Quality Management

 HACCP

 Kosher

 Halal

 FDA Registration (where applicable)

These certifications demonstrate our commitment to product safety, quality consistency, and international compliance.

OEM & Private Label Packing

Yangge Biotech offers comprehensive OEM and private-label services to help customers launch products efficiently.

OEM services include:

 Custom formulations

 Capsule filling

 Tablet manufacturing

 Powder packaging

 Bottle packaging

 Stand-up pouch packaging

 Label design support

 Custom branding

 Bulk industrial packaging

 Global export packaging

Whether you are building a new supplement brand or expanding an existing product line, we provide flexible manufacturing solutions tailored to your business needs.

Why Choose Yangge Biotech?

Choosing Yangge Biotech means partnering with a reliable ingredient manufacturer committed to quality and customer satisfaction.

Our advantages include:

 High-purity Berberine Hydrochloride Powder

 Strict quality control throughout production

 Third-party laboratory testing for every batch

 Professional R&D support

 International certifications

 Competitive factory pricing

 OEM & private-label services

 Fast global shipping

 Stable supply chain

 Responsive technical and customer support

Our mission is to deliver safe, high-quality botanical ingredients that help customers succeed in the global health and nutrition industry.

Conclusion

Berberine Hydrochloride Powder is a highly valued botanical ingredient recognized for its versatility in dietary supplements, functional foods, and nutraceutical formulations. Choosing a reliable supplier is essential to ensure product quality, purity, safety, and consistent performance.

Yangge Biotech is committed to supplying high-quality Berberine Hydrochloride Powder backed by strict quality control, comprehensive Certificates of Analysis (COA), and third-party test reports for every batch. With advanced R&D capabilities, internationally recognized certifications, flexible OEM and private-label packaging services, and dedicated customer support, Yangge Biotech provides dependable solutions for businesses worldwide.

Whether you are developing a new supplement brand or sourcing premium raw materials for large-scale production, Yangge Biotech is your trusted partner for high-quality botanical extracts. Contact us today to request samples, technical documentation, or a customized quotation, and let us help bring your products to market with confidence.

Partner with Yangge Biotech for Premium Berberine Hydrochloride Supply

Yangge Biotech is ready to help you with the creation and production of your formulations by providing you with pharmaceutical-grade materials that meet the highest quality standards. As an experienced Berberine hydrochloride manufacturer, we can give you 98% pure yellow crystalline powder that has been tested for purity using HPLC and UV. It comes in safe aluminium foil bags that keep it stable while it's being stored and shipped. Our wide range of certifications, such as ISO, HACCP, Kosher, and Halal, makes sure that we can work with a wide range of products and meet the needs of the market.

We invite purchasing managers, R&D teams, and production specialists to request detailed product datasheets, Certificates of Analysis, and samples for formulation testing. Our technical support team provides extraction methodology details, concentration specifications, and usage recommendations tailored to your specific application needs. Contact us at info@yanggebiotech.com to discuss your requirements and experience the quality, reliability, and service that distinguish Yangge Biotech in the global plant extract supply market.

FAQ

Q: Can we get some samples to test before purchasing?

A: Of course, we can provide free samples of 20 to 100 grams, but the shipping cost is at the customer's expense. The shipping cost can be deducted from the next order, or the samples can be sent through your courier account.

Q: Do your products have relevant certifications?

A: Yes, our products are certified for HALAL, ISO, HACCP, Kosher, and other certifications.

Q: What is the minimum order quantity (MOQ)?

A: Small batches of samples can be customized according to your requirements.

Q: Do you offer OEM and ODM services? Can the formula be customized based on our own?

A: Of course, we provide ODM and OEM services to many customers. Our product range includes softgels, capsules, tablets, sachets, granules, and private label services. Simply contact us and let us know your requirements. Our experienced R&D team can also develop new products with specific formulas.

Please contact us to design your own branded products.

Q: How do you handle quality complaints?

A: First, we have a comprehensive quality control SOP. We provide authoritative third-party inspection reports for almost all products before shipment to minimize the possibility of quality issues. Second, we have a comprehensive return and exchange procedure. If there is a genuine quality dispute, we will strictly follow the SOP.

Q: How do you ship? How long does delivery take?

A: For small orders, we typically use DHL, UPS, EMS, FedEx, or TNT. Delivery typically takes 3-7 days. We also offer air and sea freight services. We have a strong freight forwarding team and can provide you with a one-stop service, including DDP and DDU.

Q: What are your payment terms?

A: 100% prepayment, payable by T/T, Western Union, MoneyGram, or PayPal.

Q: What is the shelf life of your products?

A: 2 years with proper storage.

References

1. Zhang, Y., Li, X., Zou, D., Liu, W., Yang, J., Zhu, N., Huo, L., Wang, M., Hong, J., Wu, P., Ren, G., & Ning, G. (2008). Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine. Journal of Clinical Endocrinology & Metabolism, 93(7), 2559-2565.

2. Yin, J., Xing, H., & Ye, J. (2008). Efficacy of berberine in patients with type 2 diabetes mellitus. Metabolism: Clinical and Experimental, 57(5), 712-717.

3. Lee, Y. S., Kim, W. S., Kim, K. H., Yoon, M. J., Cho, H. J., Shen, Y., Ye, J. M., Lee, C. H., Oh, W. K., Kim, C. T., Hohnen-Behrens, C., Gosby, A., Kraegen, E. W., James, D. E., & Kim, J. B. (2006). Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant states. Diabetes, 55(8), 2256-2264.

4. Lan, J., Zhao, Y., Dong, F., Yan, Z., Zheng, W., Fan, J., & Sun, G. (2015). Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension. Journal of Ethnopharmacology, 161, 69-81.

5. Chang, W., Chen, L., & Hatch, G. M. (2015). Berberine as a therapy for type 2 diabetes and its complications: From mechanism of action to clinical studies. Biochemistry and Cell Biology, 93(5), 479-486.

6. Imenshahidi, M., & Hosseinzadeh, H. (2019). Berberine and barberry (Berberis vulgaris): A clinical review. Phytotherapy Research, 33(3), 504-523.